Informations sur le produit
Nom :
Benzoylacetonitrile
Synonymes :
- b-Oxohydrocinnamonitrile3-Oxo-3-phenylpropanenitrilePhenacyl cyanide
- 2-Cyanoacetophenone
- 3-Oxo-3-Phenylpropanenitrile
- 3-Oxo-3-phenylpropionitrile
- 3-Phenyl-3-ketopropionitrile
- 3-Phenyl-3-oxopropanenitrile
- Acetonitrile, benzoyl-
- Benzenepropanenitrile, β-oxo-
- Benzoylcyanomethane
- Cyanomethyl phenyl ketone
- Voir d'autres synonymes
- NSC 4713
- Phenacyl cyanide
- α-Cyanoacetophenone
- β-Oxobenzenepropanenitrile
- β-Oxobenzenepropionitrile
- ω-Cyanoacetophenone
Description :
Benzoylacetonitrile is a potent and selective inhibitor of the enzyme aromatase, which converts androstenedione to estrone and testosterone to estradiol. It has been shown to inhibit the growth of breast cancer cell lines in vitro. Benzoylacetonitrile also has anti-inflammatory activity, as it was found to inhibit HIV infection in cell culture models. The reaction mechanism has been elucidated by NMR spectroscopic data. This drug can be synthesized by reacting benzoyl chloride with acetonitrile in the presence of sodium carbonate, yielding a hydrochloride salt as an intermediate product. The final product can be obtained by hydrolysis of this intermediate ester with hydrochloric acid.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
145.16 g/mol
Formule :
C9H7NO
Degré de pureté :
Min. 95%
InChI :
InChI=1S/H3N/h1H3
Code InChI :
InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
SMILES :
N#CCC(=O)c1ccccc1
MDL:
Point de fusion :
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Code SH :
