N-(2-Boc-amino)ethyl maleimide

CAS : 134272-63-2

Ref. 3D-FB18914

Informations sur le produit

• Nom: N-(2-Boc-amino)ethyl maleimide
• Synonymes: N-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]carbamic acid 1,1-dimethylethyl ester, tert-butyl [2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]carbamate

Description

N-(2-Boc-amino)ethyl maleimide is a prodrug that hydrolyzes to form the active N-terminal amine, which can react with esterases in cells to form an intermediate reactive species. This reacts with DNA and RNA to inhibit cell growth and induce apoptosis. N-(2-Boc-amino)ethyl maleimide has been shown to have antitumor activity against HL-60 cells, which are derived from a human promyelocytic leukemia cell line.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 240.26 g/mol
• Formule: C₁₁H₁₆N₂O₄
• Degré de pureté: Min. 95%
• Couleur/Forme: Off-White Powder
• InChI: InChI=1S/C11H16N2O4/c1-11(2,3)17-10(16)12-6-7-13-8(14)4-5-9(13)15/h4-5H,6-7H2,1-3H3,(H,12,16)
• Code InChI: InChIKey=SNYRFQCLCLMCCG-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCN1C(=O)C=CC1=O