(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine

CAS : 95715-87-0

Ref. 3D-FB19415

Informations sur le produit

• Nom: (4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine
• Synonymes: (4R)-4-Formyl-2,2-dimethyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester(4R)-4-Formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxy lic acid tert-butyl ester(R)-Garner aldehyde, (4R)-4-Formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylic acid tert-butyl ester, (R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (R)-(+)-3-tert-Butoxycarbonyl-2,2-dimethyloxazolidine-4-carboxaldehyde, (R)-2,2-Dimethyl-3-tert-butoxycarbonyl-1,3-oxazolidine-4-carboxaldehyde, (R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine, (R)-4-Formyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester, (R)-Garner aldehyde, (R)-Garner's aldehyde, (R)-tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate, (S)-3-N-Boc-aminopyrrolidine, 1,1-Dimethylethyl (R)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate, 3-Oxazolidinecarboxylic acid, 4-formyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R)-, 3-Oxazolidinecarboxylic acid, 4-formyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (R)-, ent-Garner's aldehyde, tert-Butyl (4R)-4-formyl-2,2-dimethyloxazolidine-3-carboxylate, tert-Butyl (R)-(+)-4-formyl-2,2-dimethyloxazolidine-3-carboxylate, tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Description

The present invention relates to a method for the synthesis of (4R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine. The method is based on a new and efficient allylation reaction using an allyl alcohol as the electrophile. This method allows for the production of this compound in high yield and with excellent stereoselectivity. It also provides a convenient route to prepare (4R)-3-tert-butoxycarbonyl oxindole in good yield and high stereoselectivity.
This product has been shown to have antiinflammatory properties that are due to its ability to inhibit prostaglandin synthesis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 229.27 g/mol
• Formule: C₁₁H₁₉NO₄
• Degré de pureté: Min. 98%
• Couleur/Forme: Clear Liquid
• InChI: InChI=1S/C11H19NO4/c1-10(2,3)16-9(14)12-8(6-13)7-15-11(12,4)5/h6,8H,7H2,1-5H3/t8-/m0/s1
• Code InChI: InChIKey=PNJXYVJNOCLJLJ-QMMMGPOBSA-N
• SMILES: CC(C)(C)OC(=O)N1[C@@H](C=O)COC1(C)C