Boc-a-aminoisobutyric acid

CAS : 30992-29-1

Ref. 3D-FB47799

Informations sur le produit

• Nom: Boc-a-aminoisobutyric acid
• Synonymes: Boc-Aib-OHBoc-a-methylalanine, 2-(((tert-Butoxy)carbonyl)amino)-2-methylpropanoic acid, 2-(Boc-amino)isobutyric acid, 2-(tert-Butoxycarbonylamino)isobutanoic acid, 2-(tert-Butoxycarbonylamino)isobutyric acid, 2-(tert-Butoxycarboxylamino)-2-methylpropanoic acid, 2-(tert-Butyloxycarbonylamino)isobutanoic acid, 2-Methyl-2-((t-butyloxycarbonyl)amino)propionic acid, 2-Methyl-2-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Propanoic Acid, 2-[(Tert-Butoxycarbonyl)Amino]-2-Methylpropanoate, 2-[(tert-Butoxycarbonyl)amino]-2-methylpropionic acid, Alanine, N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-, Alanine, N-carboxy-2-methyl-, N-tert-butyl ester, BOC-alpha-Methylalanine, Boc-2-aminoisobutyric acid, Boc-2-methylalanine, Boc-Aib-OH, Boc-aminoisobutyric acid, Boc-α-methylalanine, N-(tert-Butoxycarbonyl)-2,2-dimethylglycine, N-(tert-Butoxycarbonyl)-2-methylalanine, N-(tert-Butoxycarbonyl)-α-methylalanine, N-(tert-Butyloxycarbonyl)-2-aminoisobutyric acid, N-BOC-α-methylalanine, N-Boc-2,2-dimethylglycine, N-Boc-2-amino-2-methylpropanoic acid, N-Boc-2-aminoisobutyric acid, N-Boc-2-methylalanine, N-Boc-α,α-dimethylglycine, N-[(1,1-Dimethylethoxy)carbonyl]-2-methylalanine, N-tert-Butoxycarbonyl-2-aminoisobutyric acid, N-tert-Butoxycarbonyl-α-aminoisobutyric acid, α-(Bocamino)isobutyric acid

Description

Boc-a-aminoisobutyric acid is a tetrapeptide pyridinium amine with a helical structure. It is synthesized by the acid conjugate of 2-aminobutyric acid and tetrazole in liquid phase, then converted to its solid form by the addition of BocCl. The synthesis of Boc-a-aminoisobutyric acid is achieved through the use of solid-phase synthesis as well as 2-aminobutyric acid. This drug has been shown to be a potent secretagogue that stimulates gastrin release in vitro and in vivo. It may also have clinical uses for gastrinomas, Zollinger Ellison syndrome, and others. Boc-a-aminoisobutyric acid's ability to stimulate secretion of gastrin is attributed to its intramolecular hydrogen bond with the amide group.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 203.24 g/mol
• Formule: C₉H₁₇NO₄
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: White Off-White Powder
• InChI: InChI=1S/C9H17NO4/c1-8(2,3)14-7(13)10-9(4,5)6(11)12/h1-5H3,(H,10,13)(H,11,12)
• Code InChI: InChIKey=MFNXWZGIFWJHMI-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NC(C)(C)C(=O)O