CK 1827452O

CAS : 873697-71-3

Ref. 3D-FC103484

Informations sur le produit

• Nom: CK 1827452O
• Synonymes: Ck-1827452, Methyl 4-[[2-fluoro-3-[N′-(6-methylpyridin-3-yl)ureido]phenyl]methyl]piperazine-1-carboxylate, Omecamtiv mecarbil, 1-Piperazinecarboxylic acid, 4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-, methyl ester

Description

CK 1827452O is a small-molecule drug that increases the glomerular filtration rate (GFR) by inhibiting the Na+,K+-ATPase. CK 1827452O has been shown to be effective in treating congestive heart failure, which may be due to its ability to increase cardiac output and reduce left ventricular end-diastolic pressure. CK 1827452O also acts on the cytosolic calcium concentration and systolic pressure, as well as natriuretic and inotropic drugs. These effects are due to its inhibition of Na+,K+-ATPase, which leads to an increase in intracellular calcium and an increase in cAMP levels.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 401.43 g/mol
• Formule: C₂₀H₂₄FN₅O₃
• Degré de pureté: Min. 95%