Comin's reagent

CAS : 145100-51-2

Ref. 3D-FC10786

Informations sur le produit

• Nom: Comin's reagent
• Synonymes: N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide), 1-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 2-[N,N-Bis(Trifluoromethanesulfonyl)Amino]-5-Chloropyridine, 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine, 2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, Bistrifluoromethylsulfonylaminochloropyridine, Comins, Comins' reagent, Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridinamine, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, N-(5-Chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide, N-(5-Chloro-2-pyridyl)-N-(trifluoromethanesulfonyl)trifluoromethanesulfonamide, N-(5-Chloro-2-pyridyl)triflimide, N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide, NSC 683533

Description

Comin's reagent is a sulfonation agent that reacts with an enolate and forms a sulfonic acid. The reaction can be used to synthesize chiral compounds. Comin's reagent is selective for the (R) configuration of acetylcholine and can be used to synthesize α-amino acids from chiral alcohols and esters. Comin's reagent is also used in the synthesis of neurotrophic or growth factor compounds, which are proteins that promote cell growth or differentiation. These functional groups are found in natural products such as nicotinic acetylcholine, thallusin, and growth factor.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 392.68 g/mol
• Formule: C₇H₃ClF₆N₂O₄S₂
• Degré de pureté: Min. 95%
• Couleur/Forme: White Powder
• InChI: InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H
• Code InChI: InChIKey=TUFGVZMNGTYAQD-UHFFFAOYSA-N
• SMILES: O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F