CH-223191

CAS : 301326-22-7

Ref. 3D-FC137662

Informations sur le produit

• Nom: CH-223191
• Synonymes: 1-Methyl-N-[2-methyl-4-[(2-methylphenyl)azo]phenyl]-1H-pyrazole-5-carboxamide

Description

CH-223191 is a potent and selective DNA polymerase chain reaction (PCR) antagonist that prevents the synthesis of double-stranded DNA. It binds to the aryl hydrocarbon receptor (AHR), which is involved in mediating toxic effects of certain environmental pollutants. CH-223191 has been shown to be an AHR antagonist, preventing activation of proinflammatory cytokines such as IL-6 and IL-8 in human hepg2 cells. This agent also inhibits the expression of proinflammatory genes, including MMP-9, COX-2, and TNF-α. Additional studies have shown that CH-223191 has lead optimization potential for anticancer drugs due to its ability to inhibit proliferation and induce apoptosis in cancer cells at low levels.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 333.40 g/mol
• Formule: C₁₉H₁₉N₅O
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder