1-9H-(Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanolphosphateHemihydrate

CAS : 610309-89-2

Ref. 3D-FC150395

Informations sur le produit

• Nom: 1-9H-(Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanolphosphateHemihydrate
• Synonymes: Carvedilol phosphate hemihydrate, 1-(9H-Carbozol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate hydrate (2:2:1), 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol phosphate hydrate (2:2:1), 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-, phosphate (salt), hydrate (2:2:1), 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-, phosphate, hydrate (2:2:1), Carvedilol Phosphate, Carvedilol dihydrogen phosphate hemihydrate, Coreg CR, Skf 105517D

Description

The chemical stability of 1-9H-(carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanolphosphate hemihydrate (1) was studied at 25°C and 40°C in phosphate buffer, pH 6.5, for 1 month. The compound is stable in the presence of water vapor and epidermal growth factor (EGF). The stability of 1 was also tested by reacting it with various solvents and excipients to determine the compatibility of 1 with other compounds. Carvedilol phosphate was found to be compatible with 1 and can be used as an excipient. A model system was designed to study the interaction of a fluorescent dye (DAPI) with 1, which showed that no fluorescence quenching occurred at concentrations up to 10 μM. A fluorescence detector was used to measure the emission spectrum of DAPI in the presence of

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 522.48 g/mol
• Formule: C₂₄H₃₁N₂O₉P
• Degré de pureté: Min. 95%