Informations sur le produit
Nom :
9-Chloroacridine
Synonymes :
- Acridine, 9-chloro-
- Ai3-52323
- Nsc 51950
Description :
9-Chloroacridine is an acridone that has potent anti-inflammatory activity. It binds to the endothelin-A receptor, which is a G protein-coupled receptor. 9-Chloroacridine also inhibits neutrophil migration and the production of reactive oxygen species. It was shown to have significant cytotoxicity in cell culture and to react with hydrochloric acid to form two chemical species: amines and protonated molecules. Molecular docking analysis has been used to show that 9-chloroacridine interacts with the enzyme dihydropteridine reductase, which is involved in pteridine synthesis. The molecule was also shown to inhibit the growth of human cancer cells in vitro. This drug may be useful as a chemotherapy agent for treatment of cancer.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
213.66 g/mol
Formule :
C13H8ClN
Degré de pureté :
Min. 95%
InChI :
InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
Code InChI :
InChIKey=BPXINCHFOLVVSG-UHFFFAOYSA-N
SMILES :
Clc1c2ccccc2nc2ccccc12
MDL:
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