9-Chloroacridine

CAS : 1207-69-8

Ref. 3D-FC151363

Informations sur le produit

• Nom: 9-Chloroacridine
• Synonymes: Acridine, 9-chloro-, Ai3-52323, Nsc 51950

Description

9-Chloroacridine is an acridone that has potent anti-inflammatory activity. It binds to the endothelin-A receptor, which is a G protein-coupled receptor. 9-Chloroacridine also inhibits neutrophil migration and the production of reactive oxygen species. It was shown to have significant cytotoxicity in cell culture and to react with hydrochloric acid to form two chemical species: amines and protonated molecules. Molecular docking analysis has been used to show that 9-chloroacridine interacts with the enzyme dihydropteridine reductase, which is involved in pteridine synthesis. The molecule was also shown to inhibit the growth of human cancer cells in vitro. This drug may be useful as a chemotherapy agent for treatment of cancer.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 213.66 g/mol
• Formule: C₁₃H₈ClN
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
• Code InChI: InChIKey=BPXINCHFOLVVSG-UHFFFAOYSA-N
• SMILES: Clc1c2ccccc2nc2ccccc12