9-(2-Chloro-ethyl)-9H-purin-6-ylamine

CAS : 19255-48-2

Ref. 3D-FC20234

Informations sur le produit

• Nom: 9-(2-Chloro-ethyl)-9H-purin-6-ylamine
• Synonymes: 9-(2-Chloroethyl)adenineNSC 50715, 9-(2-chloroethyl)-9H-purin-6-amine

Description

9-(2-Chloro-ethyl)-9H-purin-6-ylamine is a nucleotide analog. It forms hydrogen bonds with DNA bases, which may be due to the chloride ion acting as an electron acceptor. This interaction leads to cross-linking and yields low molecular weight analogs in the presence of diallylamine. 9-(2-Chloro-ethyl)-9H-purin-6-ylamine has also been shown to form hydrophobic interactions with the phosphate groups in DNA. This synthetic drug is often used in cancer chemotherapy and can be synthesized from 2,4,6-trichloropyrimidine and 1-(2 chloroethyl)pyridinium iodide.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 197.62 g/mol
• Formule: C₇H₈ClN₅
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C7H8ClN5/c8-1-2-13-4-12-5-6(9)10-3-11-7(5)13/h3-4H,1-2H2,(H2,9,10,11)
• Code InChI: InChIKey=KXIXGDZXYORBNW-UHFFFAOYSA-N
• SMILES: Nc1ncnc2c1ncn2CCCl