Cycloguanil hydrochloride

CAS : 152-53-4

Ref. 3D-FC20690

Informations sur le produit

• Nom: Cycloguanil hydrochloride
• Synonymes: 1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine hydrochlorideBN 2410Chloroguanide triazine hydrochloride
• Marque: Biosynth
• Description: Cycloguanil hydrochloride is an anti-malarial drug that inhibits the activity of dihydrofolate reductase, which is a target enzyme for many drugs. The drug is structurally similar to proguanil, but the latter has more potent activity against the parasite and better oral bioavailability. Cycloguanil hydrochloride binds to the enzyme's active site and blocks its action, thereby inhibiting essential enzymes in the synthesis of DNA. This leads to a decrease in production of malarial parasites and inhibition of their growth. Cycloguanil hydrochloride can also be used for chemoprophylaxis in falciparum malaria when combined with other drugs such as sulfadoxine or pyrimethamine.

Propriétés chimiques

• Masse moléculaire: 288.18 g/mol
• Formule: C₁₁H₁₄ClN₅•HCl
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: Powder