8-chloroquinoline

CAS : 611-33-6

Ref. 3D-FC35037

Informations sur le produit

• Nom: 8-chloroquinoline
• Synonymes: NSC 56815, Quinoline, 8-chloro-
• CAS: 611-33-6

Description

8-Chloroquinoline is an organochlorine compound that has anti-malarial, anti-parasitic, and anti-bacterial properties. It binds to the parasite's enzyme hemozoin synthase to inhibit the production of hemozoin. 8-Chloroquinoline also inhibits bacterial growth by binding to the enzyme DNA gyrase and prevents bacterial replication. The binding of 8-chloroquinoline to DNA gyrase inactivates it, thus preventing supercoiling of the bacterial DNA. This causes a structural change in the DNA helix that inhibits transcription and replication. 8-Chloroquinoline has been shown to be effective against Mycobacterium tuberculosis with minimal toxicity for liver cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 163.6 g/mol
• Formule: C₉H₆ClN
• Degré de pureté: Min. 95%