4-Cyano-3-fluorophenylboronic acid (contains varying amounts of Anhydride)

CAS : 843663-18-3

Ref. 3D-FC46550

Informations sur le produit

• Nom: 4-Cyano-3-fluorophenylboronic acid (contains varying amounts of Anhydride)
• Synonymes: (4-Cyano-3-fluorophenyl)boronic acid, Boronic acid, (4-cyano-3-fluorophenyl)-, Boronic acid, B-(4-cyano-3-fluorophenyl)-, 4-Cyano-3-fluorophenylboronic acid, 4-Borono-2-fluorobenzonitrile, 4-Cyano3-fluorophenylboronic acid

Description

4-Cyano-3-fluorophenylboronic acid is a boronic acid that is used in the treatment of primary aldosteronism. This drug inhibits the activity of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1), which converts cortisol to cortisone. It also blocks mineralocorticoid receptors, leading to decreased levels of aldosterone and increased levels of renin. 4-Cyano-3-fluorophenylboronic acid is metabolized by cytochrome P450 enzymes, with the formation of anhydride as one of its metabolites. The pharmacological effects of 4-cyano-3-fluorophenylboronic acid are due to its ability to inhibit 11βHSD1, inhibiting renal reabsorption of sodium and water.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 164.93 g/mol
• Formule: C₇H₅BFNO₂
• Degré de pureté: Min. 95%
• InChI: InChI=1S/H3N/h1H3
• Code InChI: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1ccc(B(O)O)cc1F