Cetuximab - Buffer solution

CAS : 205923-56-4

Ref. 3D-FC64978

Informations sur le produit

• Nom: Cetuximab - Buffer solution
• Synonymes: C225, Cetuximab, EGFR antibody, Erbitux, Imc 225, Imc-C 225
• CAS: 205923-56-4

Description

A monoclonal antibody against epidermal growth factor receptor (EGFR), inhibiting the binding of endogenous ligands and blocking subsequent receptor activation and intracellularr signalling. Downregulation of EGFR by cetuximab is mediated by inducing receptor internalization for degradation. In cancer, cetuximab has anti-proliferative and anti-angiogenic effects and is studied in colorectal, head and neck, squamous cell and non-small cell lung cancers.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 136581.88735
• Formule: C₆₄₈₄H₁₀₀₄N₁₇₃₂O₂₀₂₃S₃₆
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Colorless Clear Liquid