(+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

CAS : 74115-01-8

Ref. 3D-FC75160

Informations sur le produit

• Nom: (+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
• Synonymes: SKF-82958 HBr(+/-)-CHLORO-APB
• Marque: Biosynth
• Description: (+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine HBr is a model system for Parkinson's disease that has been shown to have similar effects on locomotor activity as the dopamine antagonist haloperidol. The drug enhances dopaminergic and cholinergic transmission in the brain by binding to kappa opioid receptors. This leads to an increased release of dopamine and acetylcholine that can be blocked by drugs such as naloxone and atropine respectively. (+/-)-6-Chloro-7,8-dihydroxy 3-(allyl)-1-(phenyl) 2,3,4,5 tetrahydro 1H 3 benzazepine HBr has been shown to decrease camp levels in the caudate putamen region of rats

Propriétés chimiques

• Masse moléculaire: 410.73 g/mol
• Formule: C₁₉H₂₀ClNO₂·HBr
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder