Informations sur le produit
Nom :
1-(3-Carboxypropylcarbamoyl)-5-Fluorouracil
Synonymes :
- butanoic acid, 4-[[(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)carbonyl]amino]-
- 4-{[(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)carbonyl]amino}butanoic acid
Description :
1-(3-Carboxypropylcarbamoyl)-5-Fluorouracil (1-CPC) is an antitumour agent that has been shown to inhibit tumour growth and proliferation. 1-CPC is active against solid tumours and leukaemia, and is a prodrug of 5-fluorouracil (5FU). 1-CPC has been shown to be effective in the treatment of liver cancer, as it inhibits the production of glutathione, which is needed for detoxification. It also prevents the conversion of 5FU into its active form by inhibiting the enzyme thymidine kinase. In some cases, 1-CPC can be used to monitor serum levels in patients with cirrhosis or ascites. The drug binds to cellular RNA, and can be detected by liquid chromatography.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
259.19 g/mol
Formule :
C9H10FN3O5
Degré de pureté :
Min. 95%
InChI :
InChI=1S/C9H10FN3O5/c10-5-4-13(9(18)12-7(5)16)8(17)11-3-1-2-6(14)15/h4H,1-3H2,(H,11,17)(H,14,15)(H,12,16,18)
Code InChI :
InChIKey=SRZFBVWHAXOYNE-UHFFFAOYSA-N
SMILES :
O=C(O)CCCNC(=O)n1cc(F)c(=O)[nH]c1=O
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