N-(1-Cyclohexyl-2,2,2-Trifluoroethyl)-4,5-Dihydro-1,3-Oxazol-2-Amine

CAS : 75703-13-8

Ref. 3D-FC98536

Informations sur le produit

• Nom: N-(1-Cyclohexyl-2,2,2-Trifluoroethyl)-4,5-Dihydro-1,3-Oxazol-2-Amine
• Synonymes: (-)-N-(1-Cyclohexyl-2,2,2-trifluoroethyl)-4,5-dihydro-2-oxazolamine, 2-Oxazolamine, N-(1-cyclohexyl-2,2,2-trifluoroethyl)-4,5-dihydro-, (-)-, N-(1-cyclohexyl-2,2,2-trifluoroethyl)-4,5-dihydro-1,3-oxazol-2-amine, S 8350

Description

1,3-Oxazolamine is a selective 5-HT1A receptor agonist which produces pressor and hypotensive effects. The drug also has haemodynamic effects in the spinally, producing a decrease in blood pressure. 1,3-Oxazolamine is used to treat hypotension caused by spinal cord injuries or major surgery. It has also been shown to increase arterial pressure in patients with severe heart failure. 1,3-Oxazolamine's mechanism of action is not fully understood but it may involve the activation of imidazoline receptors and antagonism of 2 adrenergic receptors (alpha1 and alpha2). Studies have shown that 1,3-oxazolamine produces maximal responses at doses lower than those required for 5HT1A agonists such as rauwolscine and ketanserin.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 250.26 g/mol
• Formule: C₁₁H₁₇F₃N₂O
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C11H17F3N2O/c12-11(13,14)9(8-4-2-1-3-5-8)16-10-15-6-7-17-10/h8-9H,1-7H2,(H,15,16)
• Code InChI: InChIKey=NZNAUUQRNQNXLR-UHFFFAOYSA-N
• SMILES: FC(F)(F)C(NC1=NCCO1)C1CCCCC1