2,6-Difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5yl)-3-(propylsulfonamido)benzamide

CAS : 1186607-05-5

Ref. 3D-FD101469

Informations sur le produit

• Nom: 2,6-Difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5yl)-3-(propylsulfonamido)benzamide

Description

2,6-Difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5yl)-3-(propylsulfonamido)benzamide is an experimental drug that targets the bRaf kinase. It has been shown to inhibit the growth of malignant cells in a number of experiments. The drug binds to the bRaf protein and blocks the kinase from binding to ATP, which prevents phosphorylation of downstream proteins involved in cell division. 2,6-Difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5yl)-3-(propylsulfonamido)benzamide also binds to other kinases such as cdc2 and cdk2, which are important for cell cycle progression.

The following product details were taken from http://

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 425.41 g/mol
• Formule: C₁₇H₁₇F₂N₅O₄S
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C17H17F2N5O4S/c1-3-6-29(26,27)24-12-5-4-11(18)13(14(12)19)16(25)21-9-7-10-15(20-8-9)22-23-17(10)28-2/h4-5,7-8,24H,3,6H2,1-2H3,(H,21,25)(H,20,22,23)
• Code InChI: InChIKey=PFHJLTOLXWXCJH-UHFFFAOYSA-N
• SMILES: CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1F