5-(2,2-Difluoroethenyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidine-2,4-Dione

CAS : 108711-80-4

Ref. 3D-FD102243

Informations sur le produit

• Nom: 5-(2,2-Difluoroethenyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidine-2,4-Dione
• Synonymes: 2'-Deoxy-5-(2,2-difluorovinyl)uridine, 5-Dfv-DU, Uridine, 2'-deoxy-5-(2,2-difluoroethenyl)-, 2'-Deoxy-5-(2,2-Difluoroethenyl)Uridine

Description

The inhibitory effect of 5-(2,2-difluoroethenyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione (AFX) on the proliferation of cells in culture was studied. AFX inhibited cell proliferation by inhibiting the kinase gene and reducing the rate of DNA synthesis. Acyclovir is a drug that is used to treat herpes simplex virus infections and other viral diseases such as chickenpox and shingles. It has been shown to be effective against a variety of viruses including HIV, influenza virus, hepatitis B virus, and herpes simplex virus type 1 (HSV-1). The mechanism of action for acyclovir is inhibition of viral DNA polymerase.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 290.22 g/mol
• Formule: C₁₁H₁₂F₂N₂O₅
• Degré de pureté: Min. 95%