Docetaxel
CAS :
Ref. 3D-FD10817
Informations sur le produit
Nom:Docetaxel
Synonymes :
- n-Debenzoyl-n-tert-butoxycarbonyl-10-deacetyl taxol
Marque:Biosynth
Description :A cytotoxic taxane and anti-microtubule agent with anti-proliferative activity. Docetaxel binds to the β-subunit of tubulin, which results in increased polymerisation and stabilisation of microtubules. The compound interferes with microtubule dynamics, which leads to the cell cycle arrest in the G2/M phase and apoptosis. The compound has significant inhibitory activity in solid tumors either alone or in combination with other chemotherapeutic agents.
Avis:Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Propriétés chimiques
Masse moléculaire :807.88 g/mol
Formule :C43H53NO14
Degré de pureté :Min. 98 Area-%
Couleur/Forme :White Powder
InChI :InChI=1S/C43H53NO14/c1-23-27(55-37(51)32(48)30(25-14-10-8-11-15-25)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)26-16-12-9-13-17-26)33-41(21-45,34(49)31(47)29(23)40(43,6)7)19-18-28-42(33,22-54-28)57-24(2)46/h8-17,27-28,30-33,35,45,47-48,53H,18-22H2,1-7H3,(H,44,52)/t27-,28+,30-,31+,32+,33-,35-,41-,42-,43+/m0/s1
Code InChI :InChIKey=DILAYYURBDUAOD-YAMYDGGLSA-N
SMILES :CC(=O)O[C@@]12CO[C@@H]1CC[C@@]1(CO)C(=O)[C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C[C@@](O)([C@@H](OC(=O)c4ccccc4)[C@H]21)C3(C)C