2,4-Difluorobenzenesulfonamide

CAS : 13656-60-5

Ref. 3D-FD12137

Informations sur le produit

• Nom: 2,4-Difluorobenzenesulfonamide
• Synonymes: 2,4-Difluorobenzenesulphonamide
• CAS: 13656-60-5

Description

2,4-Difluorobenzenesulfonamide is an inhibitor of dipeptidyl peptidase-4 (DPP-4) and a potent inhibitor of DPP-IV. It has been shown to have a pharmacokinetic profile that is dependent on the route of administration. Oral administration leads to a high concentration in the blood after about 4 hours, whereas intravenous administration leads to a rapid increase in plasma concentrations. 2,4-Difluorobenzenesulfonamide inhibits the kinase activity of DPP-IV and is selective for this enzyme. It binds to the enzyme with high affinity and specificity. The inhibition of DPP-IV by 2,4-difluorobenzenesulfonamide may lead to decreased synthesis of proinflammatory cytokines such as tumor necrosis factor α (TNFα), interleukin 6 (IL6), and IL17A.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 193.17 g/mol
• Formule: C₆H₅F₂NO₂S
• Degré de pureté: Min. 95%