Desmethyl rabeprazolethioether

CAS : 117976-91-7

Ref. 3D-FD150272

Informations sur le produit

• Nom: Desmethyl rabeprazolethioether
• Synonymes: 1-Propanol, 3-[[2-[(1H-benzimidazol-2-ylthio)methyl]-3-methyl-4-pyridinyl]oxy]-, 2-[[[4-(3-Hydroxypropoxy)-3-methyl-2-pyridyl]methyl]thio]-1H-benzimidazole, 3-({2-[(1H-benzimidazol-2-ylsulfanyl)methyl]-3-methylpyridin-4-yl}oxy)propan-1-ol, 3-[[2-[(1H-Benzimidazol-2-ylthio)methyl]-3-methyl-4-pyridinyl]oxy]-1-propanol

Description

Rabeprazole is a proton pump inhibitor (PPI) that inhibits the secretion of stomach acid. It is a racemic mixture of two enantiomers, desmethyl rabeprazole and thiomethyl rabeprazole. The pharmacokinetics of rabeprazole have been determined in healthy Chinese subjects and in human urine using liquid chromatography-mass spectrometry (LC-MS). These experiments showed that desmethyl rabeprazole has a longer half-life than thiomethyl rabeprazole. In addition, the LC-MS parameters were used to calculate the pharmacokinetic parameters of both enantiomers. Rabeprazole has been shown to inhibit donepezil metabolism, which may result in an increased exposure to donepezil.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 329.42 g/mol
• Formule: C₁₇H₁₉N₃O₂S
• Degré de pureté: Min. 95%