Detanonoate
CAS : 146724-94-9
Ref. 3D-FD16348
1mg | 177,00 € | ||
5mg | 458,00 € | ||
10mg | 652,00 € | ||
25mg | 929,00 € | ||
50mg | 1.397,00 € |
Informations sur le produit
- 2,2'-(Hydroxynitrosohydrazino)bis-ethanamineNOC-183,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazeneDiethylenetriamine/nitric oxide a dduct
- 1,1-Bis(2-Aminoethyl)-2-Hydroxy-3-Oxotriazane
- 1-Hydroxy-2-Oxo-3,3-Bis(3-Aminoethyl)-1-Triazene
- 2,2'-(2-Hydroxy-3-Oxotriazane-1,1-Diyl)Diethanaminium
- 2,2'-(Hydroxynitrosohydrazino)Bis-Ethamine
- 2,2'-(Hydroxynitrosohydrazino)Bis-Ethanamine
- 2,2′-(2-Hydroxy-2-nitrosohydrazinylidene)bis[ethanamine]
- 3,3-Bis(Aminoethyl)-1-Hydroxy-2-Oxo-1-Triazene
- Deta Nonoate
- Deta/No
- Voir d'autres synonymes
- Diethylamine NONOate
- Diethylamine diazeniumdiolate
- Diethylenetriamine Nonoate
- Ethanamine, 2,2′-(2-hydroxy-2-nitrosohydrazinylidene)bis-
- Ethanamine, 2,2′-(hydroxynitrosohydrazono)bis-
Detanonoate is a cyclase inhibitor that can induce apoptosis and inhibit the production of pro-inflammatory cytokines. Detanonoate has been shown to be minimally toxic in cell culture studies and to have a minimal effect on enzyme activity. Detanonoate also has significant cytotoxicity against tumor cells, with minimal toxicity against normal cells. It also exerts an anti-inflammatory effect through its inhibition of toll-like receptor 4, which is involved in the inflammatory response. Detanonoate has been shown to decrease tumor growth by inhibiting matrix metalloproteinase-9 (MMP-9) activity, which may be due to its ability to inhibit mitochondrial membrane potential. Detanonoate is used for the treatment of bowel disease.
Propriétés chimiques
Question d’ordre technique sur : 3D-FD16348 Detanonoate
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