4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

CAS : 844442-38-2

Ref. 3D-FD167421

Informations sur le produit

• Nom: 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide
• Synonymes: AT 7519, 1H-Pyrazole-3-carboxamide, 4-[(2,6-dichlorobenzoyl)amino]-N-4-piperidinyl-, 4-(2,6-Dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid N-(piperidin-4-yl)amide, 4-[(2,6-Dichlorobenzoyl)amino]-N-4-piperidinyl-1H-pyrazole-3-carboxamide, AT-7519(HCl), AT7519 HCl, At 7517, At 7519, At 7519M, N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide Hcl

Description

4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide is a prodrug that is hydrolyzed to the active form, 4-(2,6-dichlorobenzamido)piperidine. It is an inhibitor of fatty acid oxidation and has been shown to be a potent inhibitor of reactive oxygen species (ROS) production. 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide has been shown to inhibit colony stimulating factor 1 (CSF1), protease activity, and pharmacokinetic properties. This drug also has antiinflammatory properties and inhibits cytokine release from macrophages.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 382.24 g/mol
• Formule: C₁₆H₁₇Cl₂N₅O₂
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)
• Code InChI: InChIKey=OVPNQJVDAFNBDN-UHFFFAOYSA-N
• SMILES: O=C(NC1CCNCC1)c1[nH]ncc1NC(=O)c1c(Cl)cccc1Cl