Informations sur le produit
Nom:O-Desmethyl carvedilol
Synonymes :
- 2-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]phenolBM 14242Desmethylcarvedilol
Marque:Biosynth
Description :O-Desmethyl Carvedilol is a metabolite of Carvedilol, which is an effective oral anti-hypertensive agent. O-Desmethyl Carvedilol is a potent inhibitor of the hepatic cytochrome P450 system and inhibits the activity of human liver microsomes at concentrations of 10 μM. The LC-MS/MS method for measuring O-Desmethyl Carvedilol in urine samples has been validated and found to be accurate and precise. Clinical studies have shown that carvedilol has a profile of lipid lowering, vasodilation, and anti-ischaemic effects with relatively few side effects. Studies have also shown that carvedilol is metabolized by the liver into active metabolites such as O-desmethyl carvadiol (ODC).
Avis:Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Propriétés chimiques
Masse moléculaire :392.45 g/mol
Formule :C23H24N2O4
Degré de pureté :Min. 95%
InChI :InChI=1S/C23H24N2O4/c26-16(14-24-12-13-28-21-10-4-3-9-20(21)27)15-29-22-11-5-8-19-23(22)17-6-1-2-7-18(17)25-19/h1-11,16,24-27H,12-15H2
Code InChI :InChIKey=XAUKPPPYYOKVQJ-UHFFFAOYSA-N
SMILES :Oc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12