Dihydrocyclosporin A

CAS : 59865-15-5

Ref. 3D-FD21913

Informations sur le produit

• Nom: Dihydrocyclosporin A
• Synonymes: 6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A
• Marque: Biosynth
• Description: Dihydrocyclosporin A is an immunosuppressant, which is a cyclic undecapeptide derived from fungal metabolites, specifically from the soil fungus Tolypocladium inflatum. This compound functions through the inhibition of calcineurin, which is a crucial phosphatase involved in the activation of T-cells. By binding to the intracellular protein cyclophilin, Dihydrocyclosporin A forms a complex that inhibits calcineurin activity, subsequently blocking the transcription of interleukin-2 and other cytokines essential for T-cell proliferation.

Propriétés chimiques

• Masse moléculaire: 1,204.63 g/mol
• Formule: C₆₂H₁₁₃N₁₁O₁₂
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Powder