Dropropizine

CAS : 17692-31-8

Ref. 3D-FD22618

Informations sur le produit

• Nom: Dropropizine
• Synonymes: 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol(+/-)-Dropropizine, 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol, 3-(4-Phenylpiperazin-1-Yl)Propane-1,2-Diol, Catabex, Ditustat, Dopropizin, Katril, Larylin, Ribex, Tussilex, U.C.B. 1967, Dropropizine

Description

Dropropizine is a natural compound that has been used in the treatment of chronic cough. It has been shown to have anti-inflammatory activity and to suppress the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-8 (IL-8). Dropropizine has also been shown to inhibit the inflammatory response in squamous cell carcinoma. Toxicity studies have shown that dropropizine does not cause any long-term toxicity, even at high doses. In toxicity studies, dropropizine was administered at high doses for up to 6 months with no adverse effects observed. The LD50 of dropropizine is greater than 3 g/kg in rats and mice. Dropropizine has also been found to be safe for use in humans when administered at 10 mg/kg daily for 1 week or 5 mg/kg daily for 2 weeks.

Dropropizine inhibits the production of

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 236.31 g/mol
• Formule: C₁₃H₂₀N₂O₂
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2
• Code InChI: InChIKey=PTVWPYVOOKLBCG-UHFFFAOYSA-N
• SMILES: OCC(O)CN1CCN(c2ccccc2)CC1