1-(4,4'-Difluorobenzhydry)piperazine

CAS : 27469-60-9

Ref. 3D-FD55069

Informations sur le produit

• Nom: 1-(4,4'-Difluorobenzhydry)piperazine
• Synonymes: 1-(4,4'-Difluorobenzhydryl)Piperazine, 1-(Di-p-fluorobenzhydryl)piperazine, 1-[Bis(4-Fluorophenyl)Methyl]Piperazinediium, 4,4'-Difluorobenzhydrylpiperazine, 4-[Bis(4-fluorophenyl)methyl]piperazine, Di(4-fluorophenyl)methyl piperazine, N-(4,4-Difluorobenzhydryl)piperazine, N-(Bis(4-fluorophenyl)methyl)piperazine, Piperazine, 1-[bis(4-fluorophenyl)methyl]-, Piperazine, 1-[bis(p-fluorophenyl)methyl]-, R 19352, T 841
• CAS: 27469-60-9

Description

1-(4,4'-Difluorobenzhydry)piperazine (1-DFBP) is a potential antitumor agent that has been shown to inhibit the growth of leukemia cells. It may be an inhibitor of apoptotic cell death, as it has been shown to induce hydrogen bond formation with coumarin derivatives. 1-DFBP has also been shown to have inhibitory activities against leukemia HL-60 cells, and is a competitive inhibitor of cinnarizine. The catalytic mechanism for 1-DFBP is not known, although kinetic data suggest that it involves hydrogen bonding and/or pi stacking interactions.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 288.34 g/mol
• Formule: C₁₇H₁₈F₂N₂
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2
• Code InChI: InChIKey=TTXIFFYPVGWLSE-UHFFFAOYSA-N
• SMILES: Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1