
Vortioxetine
CAS :
Ref. 3D-FD58721

Informations sur le produit
Nom:Vortioxetine
Produit contrôlé
Synonymes :
- 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]-piperazine Vortioxetine 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
Marque:Biosynth
Description :Vortioxetine is a serotonin modulator and reuptake inhibitor which appears to be much more potent on serotonin reuptake inhibition and 5-HT3 receptor antagonism than other interactions with the 5-HT receptor family. This drug binds selectively to 5-HT receptors and inhibits the activity of serotonin reuptake transporters on presynaptic neurons, thereby increasing serotonin concentrations in the brain. It is used for the treatment of major depressive disorder (MDD)and has also been shown to be effective against depression-related symptoms such as sleep disturbances, appetite disturbance, and weight change. Vortioxetine has also been demonstrated to suppress glioblastoma in both ex vivo human tissue samples and in mice. This may indicate vortioxetine signalling cascade activation supresses cancer cell division, and could constitute an effective part of a treatment regime for glioblastoma patients.
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Propriétés chimiques
Masse moléculaire :298.45 g/mol
Formule :C18H22N2S
Degré de pureté :Min. 95%
Couleur/Forme :White Powder
InChI :InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3
Code InChI :InChIKey=YQNWZWMKLDQSAC-UHFFFAOYSA-N
SMILES :Cc1ccc(Sc2ccccc2N2CCNCC2)c(C)c1