Diethyl carboxymethylphosphonate

CAS : 3095-95-2

Ref. 3D-FD76936

Informations sur le produit

• Nom: Diethyl carboxymethylphosphonate
• Synonymes: (Diethoxyphosphinyl)acetic acid, (Diethoxyphosphoryl)Acetate, (Diethylphosphono)acetic acid, 2-(Diethoxyphosphinyl)acetic acid, 2-(Diethoxyphosphoryl)acetic acid, Acetic Acid, 2-(Diethoxyphosphinyl)-, Acetic acid, (diethoxyphosphinyl)-, Acetic acid, phosphono-, P,P-diethyl ester, Acetyl Diethyl Phosphate, Diethoxyphosphorylacetic acid, Diethyl carboxymethanephosphonate, Diethylphosphonoacetic acid, NSC 272281

Description

Diethyl carboxymethylphosphonate (DCP) is a precursor to the anti-cancer drug methotrexate. It is converted to methotrexate in the body by hydrolysis of the ester group. DCP has been shown to be effective against leukemia cells, and its cytotoxicity was increased when combined with copper chloride and hydrochloric acid. DCP binds to monoclonal antibodies that are specific for epidermal growth factor receptors, inhibiting their function. This leads to cell death by interfering with hematopoietic cell proliferation and differentiation.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 196.14 g/mol
• Formule: C₆H₁₃O₅P
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C6H13O5P/c1-3-10-12(9,11-4-2)5-6(7)8/h3-5H2,1-2H3,(H,7,8)
• Code InChI: InChIKey=DVQMPWOLBFKUMM-UHFFFAOYSA-N
• SMILES: CCOP(=O)(CC(=O)O)OCC