Informations sur le produit
- 1,3,5-Trifluoro-2,4-dichlorobenzene
- 1,3-Dichloro-2,4,6-trifluorobenzene
- Benzene, 2,4-Dichloro-1,3,5-Trifluoro-
- 2,4-Dichloro-1,3,5-trifluorobenzene
2,4-Dichloro-1,3,5-trifluorobenzene (2,4-DCTF) is a nucleophilic electrophile that can be used as a reagent in organic chemistry. It is an activating agent for chlorine and is often used to introduce the trifluoromethyl group into organic compounds. 2,4-DCTF has been shown to react with amines in the presence of base or acid to form N-substituted derivatives. The substitution pattern depends on the orientation of the amine substituents. The reaction rate increases with increasing electronegativity of the substituents and decreasing steric hindrance. 2,4-DCTF also reacts with other nucleophiles such as protonated alcohols and thiols to form addition products.