Endomorphin-2 trifluoroacetate salt

CAS : 141801-26-5

Ref. 3D-FE109150

Informations sur le produit

• Nom: Endomorphin-2 trifluoroacetate salt
• Synonymes: H-Tyr-Pro-Phe-Phe-NH2 H-YPFF-NH2, Endomorphin-2 (Human, Bovine), Ypff-Nh2, Tyr-Pro-Phe-Phe-Nh2, (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-2-phenyl-ethyl]pyrrolidine-2-carboxamide, L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide

Description

Endomorphin-2 is a cyclic peptide that is the endogenous ligand for the neurokinin-1 receptor and kappa-opioid receptors. It has been shown to have analgesic, anti-inflammatory, and antidiarrheal properties. Endomorphin-2 also has been shown to inhibit platelet aggregation and vasoconstriction in vivo. The biological activities of endomorphin-2 are similar to those of endomorphin-1, but it differs structurally in that it contains a single intramolecular hydrogen bond between the amide nitrogen of Tyr and Pro. This intramolecular hydrogen bond may be responsible for the high potency of endomorphin-2, as well as its conformational stability.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 571.67 g/mol
• Formule: C₃₂H₃₇N₅O₅
• Degré de pureté: Min. 95%