[4-(4-Ethylpiperazin-1-yl)phenyl]amine

CAS : 115619-01-7

Ref. 3D-FE125043

Informations sur le produit

• Nom: [4-(4-Ethylpiperazin-1-yl)phenyl]amine
• Synonymes: 4-(4-ethylpiperazin-1-yl)anilinebenzenamine, 4-(4-ethyl-1-piperazinyl)-, 4-(4-Ethyl-1-piperazinyl)benzenamine, 4-(4-Ethyl-Piperazin-1-Yl)-Phenylamine, 4-(4-Ethylpiperazin-1-yl)benzenamine, 4-(4-Ethylpiperazine-1-yl)aniline, 4-(4-Ethylpiperazino)Aniline, 4-(4-ethylpiperazin-1-YL)aniline, 4-(4-ethylpiperazin-1-YL)phenylamine, Akos B021943, Akos Bb-8659, Art-Chem-Bb B021943, Benzenamine, 4-(4-ethyl-1-piperazinyl)-, Timtec-Bb Sbb007132

Description

4-(4-Ethylpiperazin-1-yl)phenyl]amine (NVP-AEW541) is a novel investigational drug with potent antitumor activity. It has shown to inhibit the growth of bladder cancer cells in vitro. Mechanistically, NVP-AEW541 induces autophagy and cell death in bladder cancer cells. The drug has been tested for its efficacy in a xenograft model of bladder cancer and an orthotopic mouse model of bladder cancer. In these models, NVP-AEW541 showed potent antitumor activity, including complete tumor regression, reduced tumor weight and volume, decreased proliferation index, and increased apoptosis index.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 205.3 g/mol
• Formule: C₁₂H₁₉N₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C12H19N3/c1-2-14-7-9-15(10-8-14)12-5-3-11(13)4-6-12/h3-6H,2,7-10,13H2,1H3
• Code InChI: InChIKey=KEPUOYACJXZYTQ-UHFFFAOYSA-N
• SMILES: CCN1CCN(c2ccc(N)cc2)CC1