Etiroxate

CAS : 17365-01-4

Ref. 3D-FE23191

Informations sur le produit

• Nom: Etiroxate
• Synonymes: O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine ethyl esterDL-a-Methyl-thyroxine ethyl esterCG-635, 17365-01-4, <span class="text-smallcaps">DL</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester, <span class="text-smallcaps">DL</span>-α-Methylthyroxine ethyl ester, Cg 635, D,L-a-Methylthyroxine Ethyl Ester, Ethyl O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-alpha-methyltyrosinate, Etiroxate [INN], O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-a-methyltyrosine Ethyl Ester, Thyroxine, α-methyl-, ethyl ester, <span class="text-smallcaps">DL</span>-, Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester, a-Methyl-DL-thyroxine Ethyl Ester, tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-alpha-methyl-, ethyl ester

Description

Etiroxate is a fatty acid that inhibits the activity of cholesterol acyltransferase (CAT) and 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) in the liver. It is used as an antileukemic agent, mainly in patients with acute myelogenous leukemia. Etiroxate has been shown to be effective against psychiatric disorders, such as schizophrenia and depression, in double-blind cross-over studies on animals. Etiroxate also has a beneficial effect on cardiac function and hyperlipoproteinemia in humans. Etiroxate suppresses symptoms of these conditions by inhibiting the activity of HMGCR and CAT.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 818.95 g/mol
• Formule: C₁₈H₁₇I₄NO₄
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder