2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride

CAS : 875756-97-1

Ref. 3D-FE36315

Informations sur le produit

• Nom: 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride
• Synonymes: Hoechst 33342 trihydrochloride

Description

2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride (EPMB) is a DNA binding agent that is used in tumor detection and research into apoptosis. It has been shown to inhibit the activity of p-glycoprotein, which is an efflux pump protein, and Bcl-2 protein. EPMB has also been shown to cause apoptosis in human squamous cell carcinoma cells in a concentration dependent manner. This compound has shown potential as a treatment for cancer because it inhibits the ability of cancer cells to proliferate by binding to the NMDA receptor.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 561.93 g/mol
• Formule: C₂₇H₂₈N₆O·3HCl·xH₂O
• Degré de pureté: Min. 95%
• Couleur/Forme: Yellow Powder