2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

CAS : 16357-59-8

Ref. 3D-FE40640

Informations sur le produit

• Nom: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
• Synonymes: 1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester, 1,2-Dihydro-2-ethoxy-1-quinolinecarboxylic acid e, 1-(Ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline, 2-Ethoxy-1(2H)-quinolinecarboxylic acid ethyl ester, 2-Ethoxy-N-(ethoxycarbonyl)-1,2-dihydroquinoline, EEDQ~N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, Ethyl 1,2-dihydro-2-ethoxy-1-quinolinecarboxylate, Ethyl 2-ethoxy-1(2H)-quinolinecarboxylate, N-Carbethoxy-2-ethoxy-1,2-dihydroquinoline, N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, NSC 147831, ethyl (2R)-2-ethoxyquinoline-1(2H)-carboxylate, ethyl (2S)-2-ethoxyquinoline-1(2H)-carboxylate, ethyl 2-ethoxyquinoline-1(2H)-carboxylate, ethyl N-(2-ethoxy-1,2-dihydroquinoline)carboxylate

Description

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinolin, also known as EEDQ, is a peptide coupling reagent used to couple acyl amino acids to amino acid esters. EEDQ can be used in a one-step procedure in solution and solid-phase synthesis, achieving good yields with suppression of racemisation. EEDQ is used in the formation of antibody-drug conjugates and DNA-encoded bioconjugates formed from the reaction of an amine, a carboxylic acid and a DNA fragment. EEDQ is also an irreversible dopamine-receptor antagonist (see N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline for Pharmaceutical and Diagnostic Industries).

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 247.29 g/mol
• Formule: C₁₄H₁₇NO₃
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: White Powder
• InChI: InChI=1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
• Code InChI: InChIKey=GKQLYSROISKDLL-UHFFFAOYSA-N
• SMILES: CCOC(=O)N1c2ccccc2C=CC1OCC