9-Fluoro-3-(Fluoromethyl)-2,3-Dihydro-10-(4-Methyl-1-Piperazinyl)-7-Oxo-7H-Pyrido(1,2,3-de)-1,4-Benzothiazine-6-Carboxylic Acid

CAS : 138372-62-0

Ref. 3D-FF103549

Informations sur le produit

• Nom: 9-Fluoro-3-(Fluoromethyl)-2,3-Dihydro-10-(4-Methyl-1-Piperazinyl)-7-Oxo-7H-Pyrido(1,2,3-de)-1,4-Benzothiazine-6-Carboxylic Acid
• Synonymes: 9-Fluoro-3-(fluoromethyl)-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzothiazine-6-carboxylic acid, 9-Fluoro-3-fluoromethyl-10(N-(4'-methyl)piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3de)(1,4)benzothiazine-6-carboxylic acid, 7H-Pyrido(1,2,3-de)-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-3-(fluoromethyl)-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, 9-fluoro-3-(fluoromethyl)-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic acid

Description

Gatifloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Gatifloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Gatifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 395.42 g/mol
• Formule: C₁₈H₁₉F₂N₃O₃S
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C18H19F2N3O3S/c1-21-2-4-22(5-3-21)15-13(20)6-11-14-17(15)27-9-10(7-19)23(14)8-12(16(11)24)18(25)26/h6,8,10H,2-5,7,9H2,1H3,(H,25,26)
• Code InChI: InChIKey=YHMYZZSLDKKBQL-UHFFFAOYSA-N
• SMILES: CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2SCC4CF)CC1