4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester

CAS : 121659-86-7

Ref. 3D-FF23458

Informations sur le produit

• Nom: 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester
• Synonymes: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic acid methyl esterMethyl 2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxyl ate, 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxylic acid methyl ester, 3-Quinolinecarboxylic acid, 2-cyclopropyl-4-(4-fluorophenyl)-, methyl ester, Methyl 2-Cyclopropyl-4-(4-Fluorophenyl)Quinoline-3-Carboxylate, Methyl 2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate
• CAS: 121659-86-7

Description

4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester (CPCQ) is a hmg coa reductase inhibitor that is used in the evaluation of enzyme inhibition. CPCQ has been shown to inhibit hmg coa reductase and other enzymes, such as phosphatidylcholine acyltransferase, with IC50 values in the low micromolar range. This drug has shown no significant toxic effects on cells or animals at doses up to 200 mg/kg. The photophysical properties of this compound are fluorescence and active methylene emission, which is exhibited by its quinolinecarboxylic acid moiety.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 321.34 g/mol
• Formule: C₂₀H₁₆FNO₂
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C20H16FNO2/c1-24-20(23)18-17(12-8-10-14(21)11-9-12)15-4-2-3-5-16(15)22-19(18)13-6-7-13/h2-5,8-11,13H,6-7H2,1H3
• Code InChI: InChIKey=RNXQZVFWKIPEOJ-UHFFFAOYSA-N
• SMILES: COC(=O)c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1