Fmoc-L-aspartic acid beta-methyl ester

CAS : 145038-53-5

Ref. 3D-FF49938

Informations sur le produit

• Nom: Fmoc-L-aspartic acid beta-methyl ester
• Synonymes: Fmoc-L-Asp(OMe)-OH, (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-4-methoxy-4-oxobutanoic acid, (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methoxy-4-oxobutanoic acid, (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino]-4-methoxy-4-oxobutanoic acid, 4-Methyl hydrogen N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartate, <span class="text-smallcaps">L</span>-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-methyl ester, Fmoc-Asp(Ome)-Oh, Fmoc-Asp-Ome, Fmoc-L-Asp-Ome, Fmoc-L-Aspartic acid methyl ester, N-(9-Fluorenylmethyloxycarbonyl)-L-Aspartic acid 4-methyl ester, N-9-Fluorenylmethoxycarbonylaspartic acid β-methyl ester, N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Aspartic Acid Alpha-Methyl Ester, N-Alpha-(9-Fluoroenylmethyloxycarbonyl)-L-Aspartic Acid Alpha-Methyl Ester, N-α-Fmoc-L-aspartic acid β-methyl ester
• CAS: 145038-53-5

Description

Fmoc-L-aspartic acid beta-methyl ester is an alkali metal protecting group that can be used in peptide synthesis, peptide coupling and phase peptide synthesis. It is synthesized from the commercially available Fmoc-L-aspartic acid methyl ester and β-methylalanine. Fmoc-L-aspartic acid beta-methyl ester is a cyclic compound with a ketone group at the β position. This group can be converted to an acetyl or benzoyl group by treatment with acetic anhydride or benzoyl chloride, respectively. The protecting group may be removed by treatment with trifluoroacetic acid (TFA) in dichloromethane or dioxane. Fmoc-L-aspartic acid beta methyl ester has been used as a linker between two amino acids in 3clpro, which is a small molecule inhibitor of protein kinase C

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 369.37 g/mol
• Formule: C₂₀H₁₉NO₆
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C20H19NO6/c1-26-18(22)10-17(19(23)24)21-20(25)27-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16-17H,10-11H2,1H3,(H,21,25)(H,23,24)/t17-/m0/s1
• Code InChI: InChIKey=HSOKCYGOTGVDHL-KRWDZBQOSA-N
• SMILES: COC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O