Informations sur le produit
Nom :
3'-Fluoro-2',3'-Dideoxy-5-Iodouridine
Synonymes :
- 1-(2,3-dideoxy-3-fluoropentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione
- 2',3'-Dideoxy-3'-Fluoro-5-Iodouridine
- 2′,3′-Dideoxy-3′-fluoro-5-iodouridine
- Dre 368
- Fddiurd
- Uridine, 2',3'-dideoxy-3'-fluoro-5-iodo-
- Uridine, 2′,3′-dideoxy-3′-fluoro-5-iodo-
- 3'-Fluoro-2',3'-dideoxy-5-iodouridine
Description :
3'-Fluoro-2',3'-Dideoxy-5-Iodouridine (3'-FDU) is a nucleoside analog that inhibits the replication of HIV in vitro. 3'-FDU is an analog of uracil and binds to viral RNA, which prevents viral DNA synthesis by blocking the incorporation of nucleotides into the growing strand. The antiviral activity was found to be dose dependent. 3'-FDU showed inhibitory effects on the replication of murine sarcoma virus and guinea pig hepatoma virus in vitro. The effective dose for treatment of HIV infection was found to be 500 micrograms per kilogram body weight. 3'-FDU has also been shown to inhibit RNA synthesis and protein synthesis in human cells infected with murine leukemia virus or human T-cell leukemia virus type 1.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
356.09 g/mol
Formule :
C9H10FIN2O4
Degré de pureté :
Min. 95%
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