4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester

CAS : 53135-24-3

Ref. 3D-FH165241

Informations sur le produit

• Nom: 4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester
• Synonymes: 4-Hydroxy-2-Methyl-Pyrimidine-5-Carboxylic Acid Ethyl Ester

Description

4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester is a potent inhibitor of human telomerase. The enzyme telomerase is involved in the synthesis of telomeres, which are repetitive DNA sequences at the ends of chromosomes that protect the chromosomes from deterioration or from fusion with other chromosomes. Telomeres shorten during each cell division, and eventually become too short to protect the chromosome. This leads to chromosomal instability and cell death. 4-Hydroxy-2-methyl-pyrimidine-5-carboxylic acid ethyl ester inhibits human telomerase by binding to it and preventing telomere replication. This drug has been shown to inhibit tumor growth in mice when used in combination with chemotherapy drugs.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 182.18 g/mol
• Formule: C₈H₁₀N₂O₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C8H10N2O3/c1-3-13-8(12)6-4-9-5(2)10-7(6)11/h4H,3H2,1-2H3,(H,9,10,11)
• Code InChI: InChIKey=KTZQDIINDVWLES-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cnc(C)[nH]c1=O