Informations sur le produit
Nom :
HWY 5069
Synonymes :
- 3,4-Dihydro-2-[4-(2,2-dimethylethyl)benzyl]-6-fluoro-1-undacanylisoquinolinium bromide
Description :
HWY 5069 is an isoquinoline alkaloid that has been found to inhibit the activity of kinases. This inhibitor binds to the ATP binding site of the enzyme, blocking the transfer of phosphate groups and preventing protein phosphorylation. It has been shown to inhibit wild-type protoberberine type I kinase (PK1) and a number of mutants, including PK1B, PK2A, PK2B, PK3A, PK3B and PK4. The IC50 values for these kinases range from 0.5 nM to 7 nM. In addition to its inhibitory effects on kinases, HWY 5069 also inhibits bacterial growth by binding to ribosomes at a site that is different from the binding site for erythromycin or clindamycin.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
530.6 g/mol
Formule :
C31H45BrFN
Degré de pureté :
Min. 95%
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