20a-Hydroxy cholesterol
CAS : 516-72-3
Ref. 3D-FH23941
5mg | À demander | |
10mg | À demander | |
25mg | À demander | |
50mg | À demander | |
100mg | À demander |
Informations sur le produit
- (3b)-Cholest-5-ene-3,20-diol
- (20S)-20-Hydroxycholesterol
- (20S)-Cholest-5-ene-3beta,20-diol
- (20S)-Hydroxycholesterol
- (3Beta)-Cholest-5-Ene-3,20-Diol
- (3beta,20R)-cholest-5-ene-3,20-diol
- (3β)-Cholest-5-ene-3,20-diol
- 20-Hydroxycholesterol
- 20S-Cholest-5-ene-3β,20-diol
- 20alpha-Hydroxycholesterol
- Voir d'autres synonymes
- Cholest-5-ene-3,20-diol, (3beta)-
- Cholest-5-ene-3,20-diol, (3β)-
- Cholest-5-ene-3beta,20-diol, (20S)-
- Cholest-5-ene-3beta,20alpha-diol
- Cholest-5-ene-3β,20-diol, (20S)-
- Cholest-5-ene-3β,20α-diol
20a-Hydroxy cholesterol is a model system for studying the effects of hydroxylation on fatty acid metabolism. The addition of one hydroxyl group to the 20 carbon position in cholesterol leads to an analog, 20a-hydroxycholesterol. This compound has been shown to inhibit the enzyme activities of 3-hydroxyacyl coenzyme A dehydrogenase and acyl coenzyme A:cholesterol acyltransferase. The inhibition of these enzymes leads to decreased production of both prostaglandin E2 and leukotriene B4, which are pro-inflammatory mediators. 20a-Hydroxycholesterol has also been found to be effective in treating skin cancer and adrenocortical carcinoma by inhibiting lipid synthesis, thereby reducing cell proliferation rates.
Propriétés chimiques
Question d’ordre technique sur : 3D-FH23941 20a-Hydroxy cholesterol
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