4'-Hydroxy diclofenac

CAS : 64118-84-9

Ref. 3D-FH23980

Informations sur le produit

• Nom: 4'-Hydroxy diclofenac
• Synonymes: 2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic acid4'-Hydroxydiclofenac, 2-((2,6-Dichloro-4-hydroxyphenyl)amino)benzeneacetic acid, Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)amino]-, {2-[(2,6-Dichloro-4-Hydroxyphenyl)Amino]Phenyl}Acetic Acid

Description

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid group. The major route of elimination of diclofenac is through glucuronidation by UGT1A9 and UGT2B7. This process, which leads to the formation of a glucuronide conjugate with diclofenac, is often competitively inhibited by drugs that are substrates for these enzymes. In vivo models have shown that 5-hydroxy omeprazole inhibits the formation of the glucuronide conjugate and increases plasma levels of free diclofenac. A preparative high-performance liquid chromatography method has been developed for determining diclofenac in wastewater samples. Diclofenac is an antirheumatic drug used to treat osteoarthritis and rheumatoid arthritis. Chronic oral administration of diclofenac leads to increased concentrations in

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 312.15 g/mol
• Formule: C₁₄H₁₁Cl₂NO₃
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Powder