8-Hydroxy loxapine

CAS : 61443-77-4

Ref. 3D-FH24034

Informations sur le produit

• Nom: 8-Hydroxy loxapine
• Synonymes: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepin-8-ol
• Marque: Biosynth
• Description: 8-Hydroxy loxapine is a drug that is used as an antipsychotic. It binds to the dopamine receptor in the brain and blocks its activity, which can lead to relief of some symptoms of schizophrenia. 8-Hydroxy loxapine has been shown to be effective against anesthetized rats, with a terminal half-life of about 1 hour. In clinical trials, this drug has been shown to have a good response in patients with Parkinson's disease and other extrapyramidal disorders. 8-Hydroxy loxapine is metabolized into an n-oxide in the liver and it binds to polymerase chain reaction (PCR) primers during bioanalysis. This drug also has regulatory approval for use as a nasal spray for treatment of agitation in elderly patients with dementia who are nonverbal or minimally verbal.

Propriétés chimiques

• Masse moléculaire: 343.81 g/mol
• Formule: C₁₈H₁₈ClN₃O₂
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder
• InChI: InChI=1S/C18H18ClN3O2/c1-21-6-8-22(9-7-21)18-14-10-12(19)2-4-16(14)24-17-5-3-13(23)11-15(17)20-18/h2-5,10-11,23H,6-9H2,1H3
• Code InChI: InChIKey=VNJRIWXLPIYFGI-UHFFFAOYSA-N
• SMILES: CN1CCN(C2=Nc3cc(O)ccc3Oc3ccc(Cl)cc32)CC1