Informations sur le produit
- 4,8-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one3-(a-Acetonylbenzyl)-4,8-dihydroxycoumarin
- 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one
- 2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-
- 3-(Alpha-Acetonylbenzyl)-4,8-Dihydrocoumarin
- 3-(Α-Acetonylbenzyl)-4,8-Dihydrocoumarin
- 3-(α-Acetonylbenzyl)-4,8-dihydrocoumarin, 4-8-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
- 4,8-Dihydroxy-3-(3-Oxo-1-Phenylbutyl)-2H-1-Benzopyran-2-One
- 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
- Coumarin, 3-(α-acetonylbenzyl)-4,8-dihydroxy-
8-Hydroxy warfarin is a drug that belongs to the group of anticoagulants. It is a hydroxylated derivative of warfarin. Warfarin inhibits the synthesis of vitamin K-dependent clotting factors and the activation of vitamin K-dependent proteins, which are necessary for blood coagulation. 8-Hydroxy warfarin is a more potent inhibitor than warfarin and also has stereoselective properties. The rate of metabolism and elimination half-life of 8-hydroxy warfarin are increased in rats compared with humans, possibly due to differences in cytochrome P450 enzymes. The clinical relevance of these findings has not been determined yet.