4-Hydroxy-7-methoxycoumarin
CAS : 17575-15-4
Ref. 3D-FH24294
| 1g | Arrêté | ||
| 2g | Arrêté | ||
| 5g | Arrêté | ||
| 10g | Arrêté | ||
| 25g | Arrêté |
Informations sur le produit
Nom :
4-Hydroxy-7-methoxycoumarin
Synonymes :
- 7-Methoxy-4-hydroxycoumarin4-Hydroxy-7-methoxy-2H-1-benzopyran-2-one4-Hydroxy-herniarin
- 2H-1-Benzopyran-2-One, 4-Hydroxy-7-Methoxy-
- 7-Methoxy-4-Hydroxycoumarin
- Aurora Ka-3735
- 4-Hydroxy-7-Methoxycoumarin 97%
- 2-hydroxy-7-methoxy-4H-chromen-4-one
- 4-hydroxy-7-methoxy-2H-chromen-2-one
Description :
4-Hydroxy-7-methoxycoumarin (4OHM) is a fluorescent compound that is used as a pharmacological probe. It has been shown to activate the mitogen-activated protein kinase (MAPK) cascade, which is involved in regulating cell growth and proliferation. 4OHM also induces the release of interleukin (IL)-1β and prostaglandin E2 from human monocytes, which are involved in inflammatory diseases. 4OHM has also been shown to induce necrosis in cells with low levels of extracellular ATP by inhibiting the enzyme phosphatase 2A. This inhibition leads to increased levels of intracellular calcium ions and reactive oxygen species, leading to necrosis through activation of proteases such as calpain.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
192.17 g/mol
Formule :
C10H8O4
Degré de pureté :
Min. 95%
InChI :
InChI=1S/C10H8O4/c1-13-6-2-3-7-8(11)5-10(12)14-9(7)4-6/h2-5,11H,1H3
Code InChI :
InChIKey=MJBHLQMPKBMZSF-UHFFFAOYSA-N
SMILES :
COc1ccc2c(O)cc(=O)oc2c1
MDL:
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Code SH :
