(4S)-4-Hydroxy-L-isoleucine

CAS : 55399-93-4

Ref. 3D-FH46718

Informations sur le produit

• Nom: (4S)-4-Hydroxy-L-isoleucine
• Synonymes: (2S,4S)-2-Amino-4-hydroxy-3-methylpentanoic acid, (2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid, (2S,3R,4S)-4-Hydroxyisoleucine, (4S)-4-Hydroxy-<span class="text-smallcaps">L</span>-isoleucine, 2-Amino-2,3,5-trideoxy-3-methyl-<span class="text-smallcaps">L</span>-ribonic acid, 2-Amino-4-Hydroxy-3-Methylpentanoic Acid (Non-Preferred Name), 4-Hydroxy-L-isoleucine, <span class="text-smallcaps">L</span>-Ribonic acid, 2-amino-2,3,5-trideoxy-3-methyl-, L-4-Hydroxyisoleucine, L-erythro-Pentonic acid, 2-amino-2,3,5-trideoxy-3-methyl-, (4ξ)-, 2-Amino-2,3,5-trideoxy-3-methyl-L-ribonic acid, L-Ribonic acid, 2-amino-2,3,5-trideoxy-3-methyl-

Description

(4S)-4-Hydroxy-L-isoleucine is a novel synthetic anti-inflammatory agent that has been shown to be effective in the treatment of inflammatory bowel disease. This drug is derived from L-isoleucine and has been shown to inhibit proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin 6 (IL6). The structure of this drug was determined by X-ray crystallography. The synthesis of this compound starts with the condensation reaction between 3,5-dichloroacrylic acid and hydroxyacetone. The product is then purified by means of column chromatography, yielding 4S-(3,5-dichloroacrylic acid)-4-(hydroxyacetone)l--L-isoleucine.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 147.17 g/mol
• Formule: C₆H₁₃NO₃
• Degré de pureté: Min. 95%