(S)-5-Hydroxypiperidin-2-one

CAS : 24211-54-9

Ref. 3D-FH59583

Informations sur le produit

• Nom: (S)-5-Hydroxypiperidin-2-one
• Synonymes: 2-Piperidinone,5-hydroxy-, (S)-, 2-Piperidone, 5-hydroxy-, stereoisomer (8CI), (S)-5-Hydroxy-2-piperidinone

Description

(S)-5-Hydroxypiperidin-2-one is a chiral compound that is used in the synthesis of tofacitinib. It can be obtained by nitroaldol reaction of L-tyrosine with dimethylzinc, which yields the racemic mixture of (R)- and (S)-isomers. The stereoselective synthesis of (S) 5-hydroxypiperidin-2-one also requires the use of chiral reagents such as enantioselective catalysts or diastereoselective reagents. This compound has been shown to have anti-inflammatory properties in an animal model.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 115.13 g/mol
• Formule: C₅H₉NO₂
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C5H9NO2/c7-4-1-2-5(8)6-3-4/h4,7H,1-3H2,(H,6,8)/t4-/m0/s1
• Code InChI: InChIKey=GPRZVNYVEZZOKH-BYPYZUCNSA-N
• SMILES: O=C1CC[C@H](O)CN1