5-Hydroxymebendazole

CAS : 60254-95-7

Ref. 3D-FH61716

Informations sur le produit

• Nom: 5-Hydroxymebendazole
• Synonymes: R 19167, Carbamic acid, [5-(hydroxyphenylmethyl)-1H-benzimidazol-2-yl]-, methyl ester, Carbamic acid, N-[6-(hydroxyphenylmethyl)-1H-benzimidazol-2-yl]-, methyl ester

Description

5-Hydroxymebendazole is a benzimidazole compound that is used as an anthelmintic. It has been shown to have efficacy against a number of parasites, including those that infest the central nervous system (CNS), such as the brain tumor. 5-Hydroxymebendazole has also been shown to be effective in the treatment of clostridial infections and other diseases caused by macrolide-resistant bacteria. This molecule has been validated for use in liquid chromatography with mass spectrometry (LC-MS) for determining its concentration in urine samples. The sample preparation procedure includes extraction and derivatization of 5-hydroxymebendazole, followed by analysis using LC-MS/MS. The calibration curve was generated using standards with concentrations ranging from 0.1 µg/mL to 10 µg/mL, and validation was accomplished by comparing results obtained with this method to those obtained following the standard procedure for

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 297.31 g/mol
• Formule: C₁₆H₁₅N₃O₃
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Powder
• InChI: InChI=1S/C16H15N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9,14,20H,1H3,(H2,17,18,19,21)
• Code InChI: InChIKey=IIQKUGXEGMZCLE-UHFFFAOYSA-N
• SMILES: COC(=O)Nc1nc2ccc(C(O)c3ccccc3)cc2[nH]1